Te Whakaitinga Amene (AmDH)
Whakaahuatanga Poto:
Mō te Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): he whākōkī ka taea te whakakorikori i te whakaamoniatanga o te rōpū carbonyl me te whakaiti i a ia ki te rōpū amino. He whākōkī e whakawhirinaki ana ki te NADH coenzyme, ā, ko te NADH te kaituku hauwai. E whā ngā momo hua whākōkī AmDH (Tau ko ES-AmDH101～ES-AmDH104) i whakawhanakehia e SyncoZymes, ka taea te whakamahi i roto i te whakakorikori regioselective, stereoselective rānei o ngā aldehydes me ngā ketones.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
★ Teitei o te motuhaketanga o te papa.
★ He kaha te whiriwhiringa chiral.
★ Te tahuritanga teitei.
★ He iti ake ngā hua taha.
★ Ngā āhuatanga tauhohenga ngawari.
★ He pai mō te taiao.
➢ I te nuinga o te wā, me whakauru te pūnaha tauhohenga i te matūriki, te otinga ārai, te whākōkī, te koehaumā me te pūnaha whakaora koehaumā (hei tauira, te hukahuka me te hukahuka dehydrogenase).
➢ Me tāpiri whakamutunga te AmDH ki te pūnaha tauhohenga, i muri i te whakarerekētanga o te pH me te pāmahana ki te āhua o te tauhohenga.
Tauira 1 (Te Hanganga o ngā amine chiral e rite ana mā te amination whakaiti o ngā ketone alkyl aryl)(1):
Puritia mō ngā tau e rua i raro i te -20℃.
Kaua rawa e pā ki ngā āhuatanga tino kino pēnei i: te pāmahana teitei, te pH teitei/iti me te whakarewa waro kukū teitei.
1. Kong W, Liu Y, Huang C, et al. Angewandte Chemie International Edition, 2022: e202202264.
