Imine reductase (IRED)
Whakaahuatanga Poto:
Mo te Imine reductase
ES-IRED: He karaehe ngongo e whakakorikori ana i te whakahekenga o te herenga C=N ki te herenga CN.No te redox enzyme, me te coenzyme NADPH mo te kawe hauwai.E ai ki te manakohanga chiral o nga hua, ka taea te wehewehe ki R-IRED me S-IRED.I whakawhanakehia e Syncozymes nga reductases imine 15 (numbIRED ES-IRED-101-ES-IRED-115), ka taea te whakamahi whanui i roto i te whakahekenga regioselective me te stereoselective o imines ki te whakarite amine chiral.
Momo tauhohenga catalytic:
Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-Mēra:lchen@syncozymes.com
| Nga Enzymes | Waehere Hua | Whakatakotoranga |
| Te paura Enzyme | ES-IRED-101~ ES-IRED-114 | he huinga o 14 Imine Reductase, 50 mg ia |
| 96-Well Enzyme Screening Kit | ES-IRED-1400 | he huinga 14 Imine Reductase, 1 mg ia |
★ motuhake tïpako High.
★ He kaha te whiriwhiringa o te chiral.
★ Te hurihanga teitei.
★ He iti ake nga hua.
★ Nga tikanga tauhohenga ngawari.
★ He pai te taiao.
➢ Ko te tikanga, me uru ki roto i te punaha tauhohe he tïpako, he wairewa buffer, enzyme, coenzyme, me te pünaha whakaora hou.
➢ Ko nga momo ES-IRED katoa e rite ana ki nga ahuatanga tauhohenga tino pai me ako takitahi.
➢ Ka taea te aukati i nga mahi a ES-IRED i te papanga kukū teitei.Heoi, ka taea te whakakore i te aukati ma te taapiri puranga o te tïpako.
Tauira 1(Ko te koiora o te chiral 2-methyl pyrrolidine)(1):
Tauira 2(Ko te koiora o te amine tuarua)(2):
Tauira 3 (Whakaititia o nga Imine Porohita)(3):
Kia 2 tau ki raro -20 ℃.
Kaua rawa e pa atu ki nga ahuatanga tino kino penei: te pāmahana teitei, te pH teitei/iti me te whakarewa pararopi kukū teitei.
1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.
