-
Transaldolase (TAL)
Mō te Transaldolase
ES-TAL (Transaldolase): e pā ana ki ngā threonine transaldolases, ka taea te whakatere i te tauhohenga ki te hanga i ngā β-hydroxyphenylalanine derivatives me ngā βreonine me ngā β-benzaldehyde derivatives. Ko te TAL he whākōkī e whakawhirinaki ana ki te PLP. Kotahi anake te momo hua whākōkī TAL (Tau ko te ES-TAL101) i whakawhanakehia e SyncoZymes, ka taea te whakamahi hei hanga i te β-hydroxyphenylalanine me ōna β-derivatives.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Ketoreductase (KRED)
Mō Ketoreductase
Ngā whākōkī: He whakakorikori koiora macromolecular, ko te nuinga o ngā whākōkī he pūmua.
Ketoreductase: E kiia ana hoki ko te "Carbonyl reductase", he whākōkī e whakakorikori ana i te tauhohenga redox whakahurihuri i waenga i ngā aldehyde/ketone me ngā waipiro, ā, me whai coenzymes hei tuku H pērā i te NADH, NADPH rānei. E toru ngā kāwai matua o te KRED: Ngā Dehydrogenase/Reductases mekameka-poto (SDR), Ngā Dehydrogenases/Reductases mekameka-waenga (MDR), me ngā Aldo-KetoReductases (AKR). He rite tonu ngā mahi whakakorikori o ēnei e toru, engari he rerekē te hanganga me ngā āhuatanga.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Transaminase (ATA)
Mō te transaminase
ATA mai i SyncoZymes: E 66 ngā momo hua whākōkī ATA (Tau ko ES-ATA-101~ES-ATA-166) i whakawhanakehia e SyncoZymes. He taputapu whai hua te SZ-ATA hei whakatere i te hanganga ā-rohe me te ā-whakaaro o ngā amine chiral, ngā waikawa amino me ō rātou hua mai i ngā momo waikawa keto aliphatic me te kakara, ngā aldehyde, ngā ketone me ngā ketoses.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Nitrilase (NIT)
Mō te Nitrilase
ES-NITs: Ka huri tika i te rōpū cyanide ki te rōpū carboxyl, hei hanga waikawa carboxylic, e whakamahia whānuitia ana i roto i te rongoā, te tiaki taiao, te ahumahi matū, te tāpiri kai, te kakahu, te whakaputa ahuwhenua me ētahi atu mara.
E 40 ngā momo hua Nitrilase(NIT) (Tau ko ES-NIT-101~ES-NIT-140) i whakawhanakehia e SyncoZymes. He taputapu whai hua te ES-NIT hei whakatere i te hanganga o ngā waikawa carboxylic chiral mā te hydrolysis regio- me te stereoselective o te whānuitanga o ngā nitrile aliphatic me te kakara.Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Nitrile hydratase (NHT)
Mō ngā ES-NHT
Ngā ES-NHT: he momo metalloenzyme, e whakamākūkū ana i ngā nitrile ki roto i te amide tuatahi e rite ana. E whakamahia whānuitia ana ēnei ehara i te mea mō te hanga waikawa amino, amide, waikawa carboxylic me ō rātou hua anake, engari mō te whakarite rongoā chiral hoki. E 24 ngā momo nitrile hydratases i whakawhanakehia e SyncoZymes (Tau ko ES-NHT-101～ES-NHT-124).
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Amidase (AMD)
AMD mai i SyncoZymes: E 19 ngā momo hua whākōkī AMD (Tau ko ES-AMD-101~ES-AMD-119) i whakawhanakehia e SyncoZymes. He taputapu whai hua te SZ-AMD hei whakatere i te hanganga rohe- me te stereoselective o ngā waikawa carboxylic chiral me ō rātou hua mai i ngā momo amides aliphatic me te kakara.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Te whakahekenga o te ene (ERED)
Mō te ene reductase
Ngā ES-ERED: Nō te whānau o ngā whākōkī kōwhai tawhito e whakaiti ana i te C=C i roto i ngā pūhui α, β-kore mākū me ngā rōpū mimiti-irahiko. E whakamahia whānuitia ana ēnei i roto i te rangahau i ngā matū waikawa amino, ngā matū koiora, ngā takawaenga rongoā, ngā mea kakara me ngā poraka chiral.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Ngā Oxynitrilases (HNL)
Mō ngā oxynitrilases
ES-HNL: He momo whākōkī e whakakorikori ana i te tāpiri o te HCN ki ngā aldehyde (ketones) hei whakaputa i ngā waipiro cyanide momo R, S rānei, ka taea te huri ngāwari hei maha o ngā momo rongoā, hei takawaenga rongoā rānei mā te tikanga matū.
E 29 ngā momo hua oxynitrilase (Tau ko ES-HNL-101～ES-HNL-129) i whakawhanakehia e SyncoZymes. He taputapu whai hua te SZ-HNL ki te hanga rohe- me te stereo-selective o (R)-cyanohydrins, (S)-cyanohydrins rānei mai i ngā momo aldehydes kakara, aliphatic me heterocyclic, tae atu ki ngā ketones.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Nitro reductase (NTR)
Mō te nitro reductase
Ngā ES-NTR: He whākōkī flavo e whakakorikori ana i te whakaiti i ngā rōpū nitro e whakawhirinaki ana ki te NAD(P)H i runga i ngā pūhui nitroaromatic me te nitroheterocyclic ki ngā hydroxylamino me/ranei ngā amino derivatives. E whakamahia whānuitia ana ēnei i roto i te hanga rauropi o te hydroxylamine kakara me te amine kakara, te rongoā pukupuku, te kimi koiora me te whakahekenga o ngā poke taiao. E 12 ngā momo hua Nitro reductase (NTR) (Tau ko ES-NTR-101~ES-NTR-112) i whakawhanakehia e SyncoZymes.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Aldolase (DERA)
ES-DERA: Ka taea te whakakorikori i te tāpiritanga stereoselective o ngā ketone kaituku ki ngā aldehyde kaiwhiwhi. Heoi anō, ka taea te whakahaere i te tauhohenga i roto i te wairewa pH kūpapa me te kore he tikanga tiaki motuhake. Nō te akomanga I aldolase rātou, e hanga ana i te turanga Shiff i roto i te tukanga whakakorikori. Ka honoa te papa ki te rōpū amino o te pae hohe hei tīmata i te pakaru me te hanganga o te here. Ko te rerekētanga i waenga i ngā DERA me ētahi atu aldolases ko ngā papa e whakakorikorihia ana e rātou he aldehyde, ā, ka taea te whai i te whakapūpūtanga aldehyde tonu.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Te monooxygenase cytochrome P450 (CYP)
Mō CYP
ES-CYP: He momo whākōkī redox me te mercaptan-heme hei pokapū hohe hei whakatere i te whakawhiti hāora. He oxygenase whakamutunga ēnei, ā, me heme hei whakahohe i te hāora.
Ka whakakorikori te cytochrome P450 monooxygenase i te waikura, te epoxidation me te hydroxylation o te alkyl, te hydroxylation me te waikura o te haukini, te waikura o te whanariki, te dealkylation (hāora, whanariki, haukini), te tango waikura, te deamination me te dehalogenation.
E waru ngā momo hua cytochrome P450 monooxygenase (Tau ko ES-CYP-101～ES-CYP-108) i whakawhanakehia e SyncoZymes.Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
-
Te waipiro oxidase (AOX)
Mō te waipiro oxidase
ES-AOXs: Ka taea e ēnei whākōkī te whakakorikori i te waikura o ngā waipiro ngako, o ngā aryl-alcohol rānei hei hanga aldehydes. Ka whakamahia e rātou te hāora ngota engari kāore e hiahiatia he cofactor tāpirihia ki waho, ā, ka puta te hauwai peroxide.
E ono ngā momo hua waipiro oxidase (Tau ko ES-AOX-101~ES-AOX-106) i whakawhanakehia e SyncoZymes. Ko ES-AOX101 me ES-AOX102 e pai ake ana ki ngā matū waipiro aliphatic, ko ES-AOX103~ES-AOX105 e pai ake ana ki ngā matū waipiro kakara, ā, ko ES-AOX106 te cholesterol oxidase. He taputapu whai hua a SZ-AOX hei whakatere i te waikura o ngā waipiro ngako, o ngā aryl-alcohol rānei hei whakaputa aldehydes.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
