β-Nicotinamide Mononucleotide (NMN)
Nō nā tata nei, he rongo pai kei te ao o te NMN - whai muri i te arotake pakari a te komiti ngaio o te whakahaere mana o te US Food and Drug Administration (FDA), kua whakaaetia ngā rauemi mata NMN o Shangke Biopharmaceutical (Shanghai) Co., Ltd. (e kiia nei ko "Shangke Bio") e te United States FDA. Mā te whakaaetanga NDI e whakaū ka taea te whakamahi mana i ngā rauemi mata NMN ki te hanga, te hoko me te whakatairanga i ngā tāpiringa kai i te United States, ā, ka kitea i te paetukutuku mana o te FDA hei rauemi mata tāpiringa kai hou, nama 1247.
Ko te FDA NDI te pūnaha tiwhikete tino nui i te mākete o Amerika. Mā te whiwhi i tēnei tiwhikete, ehara i te mea ko te haumaru me te kounga o ngā hua a Shangke Bio anake te mea e tika ana.e tino mōhiotia ana, engari e whai hua ana hoki ki te whanaketanga paerewa tonu o te umanga NMN i te wā roa.
| Ingoa Matū | β-Nikotinami Mononukleotida |
| Ngā kupu taurite | NIKOTINAMIRA-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Tau CAS | 1094-61-7 |
| Taumaha ngota | 334.22 |
| Tātai Ngota | C11H15N2O8P |
| EINECS ingoa: | 214-136-5 |
| Te pūwāhi rewa | 166 °C (whakaheke) |
| pāmahana rokiroki | -20°C |
| te wairewatanga | DMSO (Paku, Wera), Methanol (Paku), Wai (Paku) |
| puka | Totoka |
| tae | Mā ki te Kōwhai |
| Merck | 13,6697 |
| BRN | 3570187 |
| Te pumau: | Tino hihiko |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Tūemi Whakamātautau | Ngā Whakatakotoranga |
| Āhua | Paura tioata mā ki te mā-parauri |
| Te ihirangi konutai | ≤1% |
| Uara pH (100mg/ml) | 2.0~4.0 |
| Te parakore | ≥99.0% |
| Te nui o te wai | ≤1% |
| Ngā konganuku taumaha | <10ppm |
| Āheni | <0.5ppm |
| Ārahi | <0.5ppm |
| Merekurai | <0.1ppm |
| Kāmiuma | <0.5ppm |
| toenga whakarewa | Etanora≤1000ppm |
| Tapeke o ngā moroiti hauātea | <750cfu/g |
| Rewena me te Pokepokea | <25cfu/g |
| Ko te katoa o te koriform | ≤0.92MPN/g |
| E. Coli | Kino |
| Salmonella | Kino |
| Staph. Aureus | Kino |
| Whakamātautau (i runga i te pūtake waikore) | ≥99.0% |
| Te tere tātari | ≥95% |
| Kīanga papatipu | Pūrongo mō ngā mōhiohio |
Mōkihi:Pounamu, putea konumohe, 25kg/Pahu Kāri, kia rite rānei ki te hiahia o te kiritaki.
Āhuatanga Rokiroki:Rongoā ki roto i ngā ipu piripono, ātete ki te mārama, mō te rokiroki roa, rongoā ki te 2~8°C, ki raro iho rānei.
Ko te Nicotinamide Mononucleotide (NMN) he putanga auaha o te huaora B3, he takahanga kotahi te mua o te NAD+ (Nicotinamide Adenine Dinucleotide). Ko te NMN te whakaora NAD+ pūtau tuatahi kua whakamātauhia he whai hua ki te whakaora i ngā pūtau i roto i te tinana ora.
Ko te Nicotinamide Adenine Dinucleotide (NAD) tētahi o ngā ngota tino nui, tino whakamere hoki o te tinana. E hiahiatia ana mō te neke atu i te 500 ngā tauhohenga whākōkī, ā, e whai wāhi nui ana ki te whakahaere i te nuinga o ngā tukanga koiora nui (Ansari and Raghava, 2010). Engari, mā tēnei ka taea e tātou te ora hauora me te roa ake o te ora.
Kei te noho te Nicotinamide Adenine Dinucleotide (NAD) i roto i tōna āhua waikura (NAD+) i tōna āhua whakaiti rānei (NADH), he hononga matua ēnei o te maha o ngā oxireductases.
Ko SyncoZyems te tuatahi ki te whiwhi i te whakaaetanga a te FDA NDI NMN mō te hanga rauemi mata, ā, e tohu ana i te mana o te FDA e whakaae ana ki te NMN hei momo rauemi hou ka taea te tīmata te whakaae me te whakaaetia mō ngā kai tāpiringa kai i roto i te United States.
