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Ngā Oxynitrilases (HNL)
Mō ngā oxynitrilases
ES-HNL: He momo whākōkī e whakakorikori ana i te tāpiri o te HCN ki ngā aldehyde (ketones) hei whakaputa i ngā waipiro cyanide momo R, S rānei, ka taea te huri ngāwari hei maha o ngā momo rongoā, hei takawaenga rongoā rānei mā te tikanga matū.
E 29 ngā momo hua oxynitrilase (Tau ko ES-HNL-101～ES-HNL-129) i whakawhanakehia e SyncoZymes. He taputapu whai hua te SZ-HNL ki te hanga rohe- me te stereo-selective o (R)-cyanohydrins, (S)-cyanohydrins rānei mai i ngā momo aldehydes kakara, aliphatic me heterocyclic, tae atu ki ngā ketones.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Nitro reductase (NTR)
Mō te nitro reductase
Ngā ES-NTR: He whākōkī flavo e whakakorikori ana i te whakaiti i ngā rōpū nitro e whakawhirinaki ana ki te NAD(P)H i runga i ngā pūhui nitroaromatic me te nitroheterocyclic ki ngā hydroxylamino me/ranei ngā amino derivatives. E whakamahia whānuitia ana ēnei i roto i te hanga rauropi o te hydroxylamine kakara me te amine kakara, te rongoā pukupuku, te kimi koiora me te whakahekenga o ngā poke taiao. E 12 ngā momo hua Nitro reductase (NTR) (Tau ko ES-NTR-101~ES-NTR-112) i whakawhanakehia e SyncoZymes.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: Ka taea te whakakorikori i te tāpiritanga stereoselective o ngā ketone kaituku ki ngā aldehyde kaiwhiwhi. Heoi anō, ka taea te whakahaere i te tauhohenga i roto i te wairewa pH kūpapa me te kore he tikanga tiaki motuhake. Nō te akomanga I aldolase rātou, e hanga ana i te turanga Shiff i roto i te tukanga whakakorikori. Ka honoa te papa ki te rōpū amino o te pae hohe hei tīmata i te pakaru me te hanganga o te here. Ko te rerekētanga i waenga i ngā DERA me ētahi atu aldolases ko ngā papa e whakakorikorihia ana e rātou he aldehyde, ā, ka taea te whai i te whakapūpūtanga aldehyde tonu.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te monooxygenase cytochrome P450 (CYP)
Mō CYP
ES-CYP: He momo whākōkī redox me te mercaptan-heme hei pokapū hohe hei whakatere i te whakawhiti hāora. He oxygenase whakamutunga ēnei, ā, me heme hei whakahohe i te hāora.
Ka whakakorikori te cytochrome P450 monooxygenase i te waikura, te epoxidation me te hydroxylation o te alkyl, te hydroxylation me te waikura o te haukini, te waikura o te whanariki, te dealkylation (hāora, whanariki, haukini), te tango waikura, te deamination me te dehalogenation.
E waru ngā momo hua cytochrome P450 monooxygenase (Tau ko ES-CYP-101～ES-CYP-108) i whakawhanakehia e SyncoZymes.Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te waipiro oxidase (AOX)
Mō te waipiro oxidase
ES-AOXs: Ka taea e ēnei whākōkī te whakakorikori i te waikura o ngā waipiro ngako, o ngā aryl-alcohol rānei hei hanga aldehydes. Ka whakamahia e rātou te hāora ngota engari kāore e hiahiatia he cofactor tāpirihia ki waho, ā, ka puta te hauwai peroxide.
E ono ngā momo hua waipiro oxidase (Tau ko ES-AOX-101~ES-AOX-106) i whakawhanakehia e SyncoZymes. Ko ES-AOX101 me ES-AOX102 e pai ake ana ki ngā matū waipiro aliphatic, ko ES-AOX103~ES-AOX105 e pai ake ana ki ngā matū waipiro kakara, ā, ko ES-AOX106 te cholesterol oxidase. He taputapu whai hua a SZ-AOX hei whakatere i te waikura o ngā waipiro ngako, o ngā aryl-alcohol rānei hei whakaputa aldehydes.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te whakapūngao waikawa amino D-Amino (D-AADH)
Mō te D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): he whākōkī ka taea te whakaiti i te waikawa 2-keto ki te waikawa amino-D e rite ana. Me whai NADP(H) me te kaituku haukini kore-waro (pēnei i te haukini, te ion haukini rānei) hei tauhohenga. E 17 ngā momo D-amino acid dehydrogenase (Tau ko ES-DAADH-101~ ES-DAADH-117) i whakawhanakehia e SyncoZymes.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Esterase me te Lipase (PLE me te CALB)
Mō Esterase me Lipase
ES-PLE: He momo hydrolases e whakakorikori ana i te hanganga me te pakaru o ngā here ester. Ka taea e rātou te whai wāhi ki ngā momo tauhohenga matū koiora maha, pērā i te esterification, te transesterification me te hydrolysis. He whānuitia te whakamahinga i roto i ngā mara maha pērā i te tukatuka kai, te ahumahi matū, te rongoā koiora, te rongoā chiral me te maimoatanga taiao.
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te haurore epoxide (EH)
Mō te epoxide hydrolase
Ko te EH he ether hydrolase e whakateretere ana i te hydrolysis stereoselective o ngā racemic epoxides hei whakaputa i te 1, 2-diol me ngā optically active epoxides, ka taea te whakamahi mō te whakataunga chiral o ngā epoxides, te whakarite rānei i ngā chiral diols. He whānuitia te whakamahinga i roto i te rongoā me ētahi atu mara. E toru ngā momo hua epoxide hydrolases (Tau ko ES-EH-101～ES-EH-103) i whakawhanakehia e SyncoZymes. He taputapu whai hua te ES-EH hei whakateretere i te hanganga o ngā waipiro chiral mā te hydrolysis stereoselective o ngā aliphatic me ngā aromatic epoxides.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te whakapūmau i te hauwaiora (FDH)
Mō te Formate dehydrogenase
ES-FDH (Formate dehydrogenase): Ka whakakorikori te FDH i te tangohanga o te ammonium formate hei whakaputa i te hauhā waro me te haukini, ka whakaiti i te NAD ki te NADH me te NAD hei kaiwhiwhi irahiko. He maha ngā wā ka whakamahia te FDH mō te whakaora i te coenzyme NADH. E whā ngā momo hua whākōkī FDH (ES-FDH-101~ES-FDH-104) i whakawhanakehia e SyncoZymes, ā, ko te ES-FDH102 te mea tino kaha te mahi, ā, koia te FDH e tino taunakitia ana.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te whakahekenga hukahuka (GDH)
Mō te Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): Ka whakakorikori te GDH i te tangohanga o te hukahuka hei whakaputa waikawa kurukoni (lactone), ka whakaiti i te NAD(P)+ ki te NAD(P)H, me te NAD(P)+ hei kaiwhiwhi irahiko. He maha ngā wā ka whakamahia te GDH mō te whakaora i te coenzyme NAD(P)H i roto i ngā mara biocatalysis me ētahi atu whākōkī matua. E 10 ngā momo hua whākōkī GDH (ES-GDH-101~ES-GDH-110) i whakawhanakehia e SyncoZymes, i roto i ēnei ko te ES-GDH110 te mea tino kaha te mahi, ā, ko ia te GDH e tino taunakitia ana.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Mō te Monoamine oxidase
ES-MAO (Monoamine oxidase): Ka whakakorikori te MAO i te whakakorenga waikura o ngā monoamine hei whakaputa i te hauwai peroxide, te haukini me ngā aldehydes e rite ana. I roto i te tukanga whakakorikori, e hiahiatia ana te hāora hei waikura. E ono ngā momo hua whākōkī MAO (Tau ko ES-MAO-101～ES-MAO-106) i whakawhanakehia e SyncoZymes, ka taea te whakamahi i roto i te whakakorenga waikura o ngā pūhui monoamine.
Momo tauhohenga whakakorikori:
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
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Te Whakaitinga Hauota o te Lactate (LDH)
Mō te Lactate dehydrogenase
Kotahi te momo hua whākōkī LDH (Tau ko ES-LDH) i whakawhanakehia e SyncoZymes. Ka taea e te LDH te whakakorikori i te whakahekenga o te pyruvate ki te waikawa L-lactic, te whakahekenga rānei o ētahi atu waikawa α-keto rite. I roto i te tukanga whakakorikori, he mea nui te NADH hei kaikawe hauwai.
Momo tauhohenga catalytic lactate dehydrogenase
Waea Pūkoro/Wechat/WhatsApp: +86-13681683526
Ī-mēra:lchen@syncozymes.com
